“Nothing Really Matters” is a song by American recording artist Madonna, which was released as the fifth and last single off her seventh studio album Ray of Light (1998). The song was written by Madonna and Patrick Leonard and was produced by Madonna, William Orbit and Marius De Vries.  This copy of the CD single has been hand signed by Madonna in blue ink on the front cover of the CD inlay card.

The song was lyrically written about Madonna’s creative process where people had dissecting and judged her. According to Madonna, the song was inspired by her daughter Lourdes Leon. Musically, the song is a midtempo dance-pop song, which incorporates house music with some ambient andelectropop music. The song received generally positive reception from many music critics, who praised Madonna’s lyrics for being inspirational towards her fans and family. After the release, the song received generally modest charting success in the U.S., where the song had peaked at 93, becoming Madonna’s lowest charting single in the Hot 100 to date. However, the song managed to peak at number one on the Hot Dance Club Play, and peaked at number 27 on the Hot Singles Sales chart in the U.S.

The music video of the song was directed by Johan Renck and was inspired by the book Memoirs of a Geisha, with Madonna depicted as a geisha. The costumes, which were designed by Jean-Paul Gaultier were also used in her Drowned World Tour. The song was performed at the 1999 Grammy Awards, during which Madonna was also inspired by the geisha look.